Aromatase pathway mediates sex change in each direction
نویسندگان
چکیده
منابع مشابه
Inhibition of Aromatase Induces Partial Sex Change in a Cichlid Fish: Distinct Functions for Sex Steroids in Brains and Gonads.
Sex steroids are major drivers of sexual development and also responsible for the maintenance of the established gender. Especially fishes exhibit great plasticity and less conservation in sex determination and sexual development compared to other vertebrate groups. In addition, fishes have a constant sex steroid production throughout their entire lifespan, which makes them particularly suscept...
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This study investigated whether undifferentiated germ and/or somatic stem cells remain in the differentiated ovary of a species that does not undergo sex changes under natural conditions and retain their sexual plasticity. The effect of aromatase inhibitor (AI)-treatment on sexually mature female zebrafish was examined. A 5-month AI treatment caused retraction of the ovaries after which testes-...
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ژورنال
عنوان ژورنال: Proceedings of the Royal Society B: Biological Sciences
سال: 2005
ISSN: 0962-8452,1471-2954
DOI: 10.1098/rspb.2005.3097